Wellbutrin

Modern antidepressants are divided into three groups - in line with the what effect they have on the biochemical processes of our brain. There are also anti-depressants, which do not belong to any of these groups.

To this group of antidepressants belong to the earliest formulations with antidepressiruyuschim effect, which were synthesized in the 50 years of last century. Its name - "tricyclic" they received because of its structure, which is based on triple carbon ring. This group of drugs include imipramine, amiltriptilin and Nortriptyline.

Tricyclic antidepressants increase in our brain concentration of neurotransmitters such as serotonin and noripinefrin, by reducing the absorption of these neurons. The drugs in this group is different - for example, amitriptyline has a calming effect, and imipramine, on the contrary, stimuliruyuschim.TTsA is faster than other groups - in some cases, positive mood changes can occur within a few days after starting, though all very individual, and sometimes stable results are observers only a few months of reception.

IMOA inhibit the operation of the enzyme monoamine oxidase, contained in the nerve endings. This enzyme destroys neurotransmitters such as serotonin and noripinefrin that affect our mood. MAOIs are the main feniuzin, tranylcypromine and izokarboksazid.

Usually MAOI appoint those who do not get better after taking tricyclic antidepressants. They are also often appointed with atypical depression - disorder, some of whom opposed the typical symptoms of depression (many people sleep and eat, he feels no worse than the mornings and evenings). In addition, as MAOIs have a stimulating rather than calming effect, they are preferable to TCA for the treatment of dysthymia - a small depression.

The most recent class of antidepressants, which became popular with fewer side effects compared with drugs of the two previous groups. But IIPS has a drawback, not so noticeable in countries with developed economies, but is a stumbling block for Russia - a fairly high price. (Prices for antidepressants developed in recent years, may reach 1500-2000 rubles). The effect of these drugs are based on increasing the supply of the brain serotonin, a mediator that regulates our mood.

IIPS got its name in connection with the mechanism of action - they block the reuptake of (re-uptake) of serotonin in the synapse (the space between neurons), resulting in the concentration of this neurotransmitter is increased. Inhibitors act on serotonin, without affecting other neurotransmitters, so almost no side effects. This group includes fluoxetine (Prozac), paroxetine (Paxil), fluvoxamine (Luvoks) and sertraline (Zoloft).